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The complex includes remnants of a ruined palace, fortifications, gardens, ponds, and fountains. Koishikawa Korakuen Gardens, Tokyo: It is considered to be one of Tokyo's oldest and best gardens. It has reproductions of famous landscapes in miniature, made using stones, trees and manmade hills to replicate Japanese and Chinese scenery. Monet's Gardens, France: Artist Claude Monet's garden in Giverny is straight out of his paintings. It has a flower garden and a Japanese-inspired water garden. Tivoli Gardens, Denmark: It is located in Tivoli, the second-oldest theme park in the world.At night, the gardens are illuminated beautifully and there are stage performances. Las Pozas, Mexico: This garden (Las Pozas means ‘the wells) in Xilitla is filled with surreal structures and located 2,000 feet above sea level. It was created by English poet Edward James in a rainforest. There are waterfalls alongside towering structures. Garden of Dreams, Nepal: This beautiful garden has fountains and a pavilion for the six seasons of Nepal: summer, monsoon, autumn, pre-winter, winter and spring. A new study has uncovered why some people that have brain markers of Alzheimer's never develop classic dementia that others do. Alzheimer's disease is the most common form of dementia. People suffering from Alzheimer's develop a buildup of two proteins that impair communications between nerve cells in the brain - plaques made of amyloid beta proteins and neurofibrillary tangles made of tau proteins. Intriguingly, not all people with those signs of Alzheimer's show any cognitive decline during their lifetime. The question became, what sets these people apart from those with the same plaques and tangles that develop the signature dementia? In order to answer this question, the researchers at The University of Texas used high-throughput electrophoresis and mass spectrometry to analyse the protein composition of synapses isolated from frozen brain tissue donated by people who had participated in brain ageing studies and received annual neurological and neuropsychological evaluations during their lifetime. The participants were divided into three groups - those with Alzheimer's dementia, those with Alzheimer's brain features but no signs of dementia and those without any evidence of Alzheimer's. The results showed that resilient individuals had a unique synaptic protein signature that set them apart from both demented AD patients and normal subjects with no AD pathology. This unique protein make-up may underscore the synaptic resistance to amyloid beta and tau, thus enabling these fortunate people to remain cognitively intact despite having Alzheimer's-like pathologies. Turns out, the consequences of healthcare-associated infections (HAIs) reach well beyond patients' physical health, souring social relationships, and leading some healthcare providers (HCP) to distance themselves from affected patients. HAIs are infections that patients get while receiving treatment for medical or surgical conditions, and many HAIs are preventable.

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